Global burden of bacterial antimicrobial resistance in 2019: a systematic analysis

Bacterial antimicrobial resistance (AMR)—which occurs when changes in bacteria cause the drugs used to treat infections to become less effective—has emerged as one of the leading public health threats of the 21st century. The Review on Antimicrobial Resistance, commissioned by the UK Government, argued that AMR could kill 10 million people per year by 2050.

Global burden of bacterial antimicrobial resistance in 2019: a systematic analysis2022-08-03T13:00:05+00:00

Natureza Patents New Antibiotics

Natureza® Develops a Transformative New Class of Antibiotics that Overcomes Bacterial Resistance. We have successfully shown these coated Fatty Acids work as effective antibiotics in in vitro and in vivo, with activity against some of the most drug resistant pathogens. Uniquely, bacteria exposed to them do not develop resistance.

Natureza Patents New Antibiotics2022-08-03T13:44:13+00:00

Lack of new antibiotics threatens global efforts to contain drug-resistant infections.

Declining private investment and lack of innovation in the development of new antibiotics are undermining efforts to combat drug-resistant infections, says the World Health Organization (WHO). Two new reports reveal a weak pipeline for antibiotic agents. The 60 products in development (50 antibiotics and 10 biologics) bring little benefit over existing treatments and very few target the most critical resistant bacteria (Gram-negative bacteria).

Lack of new antibiotics threatens global efforts to contain drug-resistant infections.2022-08-03T13:04:05+00:00

WHO to World: The Foundation of Modern Medicine is Crumbling

The WHO has recognised a number of antibiotic-resistant pathogens as posing the greatest threat to human health. It further concluded that mortality and morbidity from resistant infections is on the rise globally, the clinical anti-bacterial pipeline remains insufficient, and the pipeline outlook remains bleak (WHO 2019).

WHO to World: The Foundation of Modern Medicine is Crumbling2022-08-03T13:48:25+00:00

Opinion: We Need More than New Antibiotics to Fight Resistance

Metabolic disrupters, phages, and other approaches are going to be needed to treat the broadest possible range of patients infected by bacterial pathogens resistant to multiple drugs. In 1924 President Coolidge's youngest son developed a blister on a toe playing tennis. The blister became infected with staph, and he died a week later at just 16 years old. Two decades later, penicillin could have saved him, but this drug is now useless against staph because of drug resistance, which has now become a broader crisis in medicine.

Opinion: We Need More than New Antibiotics to Fight Resistance2022-08-03T13:54:10+00:00

Antibiotic Resistance: A Rundown of a Global Crisis

The advent of multidrug resistance among pathogenic bacteria is imperiling the worth of antibiotics, which have previously transformed medical sciences. The crisis of antimicrobial resistance has been ascribed to the misuse of these agents and due to unavailability of newer drugs attributable to exigent regulatory requirements and reduced financial inducements.

Antibiotic Resistance: A Rundown of a Global Crisis2022-08-03T14:08:38+00:00

The Rise of Superbugs: Facing the Antibiotic Resistance Crisis

While medical research has helped us overcome many health threats, we now face a new type of crisis: Many dangerous bacteria are becoming resistant to the drugs meant to fight them. Healthcare professionals antibiotics to treat many forms of bacterial infection — from those that are mild to those that are potentially life threatening. For the most part, antibiotics have proved to be a crucial ally in the fight for health, but over the past few years, these drugs have begun to lose their footing in their confrontation with bacteria.

The Rise of Superbugs: Facing the Antibiotic Resistance Crisis2022-08-03T14:22:43+00:00

The World Is Running Out Of Antibiotics, WHO Report Confirms

A report, Antibacterial agents in clinical development, analizes the antibacterial clinical development pipeline launched by WHO, shows a serious lack development new antibiotics to combat the growing antimicrobial resistance threat. Most of the drugs currently in the pipeline are modifications of existing classes of antibiotics and are only short-term solutions. The report found very few potential treatment options for antibiotic-resistant infections, including drug-resistant TB which kills about 250,000 annually.

The World Is Running Out Of Antibiotics, WHO Report Confirms2022-08-03T14:57:17+00:00

Review on Antimicrobial Resistance

The Review on Antimicrobial Resistance (AMR), was commissioned in July 2014 by the UK Prime Minister, who asked economist Jim O’Neill to analyse the global problem of rising drug resistance and propose concrete actions to tackle it internationally. The Review on AMR was jointly supported by the UK Government and Wellcome Trust, although operated with full independence from both. The final report and recommendations were published in the summer of 2016.

Review on Antimicrobial Resistance2022-08-03T15:06:23+00:00

Innovative Ways to Pay for New Antibiotics Will Help Fight Superbugs

Antibiotics are the most important drug class in human history. Without them, minor infections could turn deadly. Heart surgery, cancer treatment, and virtually everything else that happens in a hospital would be far more dangerous than it is today. But if we keep taking them for granted, and fail to provide innovative approaches to funding the development of new antibiotics, drug-resistant microbes will get the upper hand.

Innovative Ways to Pay for New Antibiotics Will Help Fight Superbugs2022-08-03T13:13:18+00:00
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